Antiretroviral Therapy and Adverse Skeletal Effects
نویسندگان
چکیده
منابع مشابه
Common adverse effects of antiretroviral therapy for HIV disease.
Family physicians are treating patients infected with human immunodeficiency virus in their practices more often. Long-term complications of this disease are multifactorial and can be related to the virus itself or to adverse effects of antiretroviral therapy. Each drug class has side effects: nucleoside/nucleotide reverse transcriptase inhibitors are associated with lactic acidosis, lipodystro...
متن کاملAntiretroviral drugs, genotoxicity, and adverse effects
ents and also specifically for reducing the risk of mother-to-child transmission of HIV in relation to pregnancy and childbirth. In this report we review the consequences that have been demonstrated for children following in utero exposure of these drugs. We focus mainly on the groups of drugs that are known to be potentially genotoxic (NRTIs). The risk of cancer-development is the concern that...
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The complexity of antiretroviral therapy, coupled with the lifelong duration of treatment, presents the need for extensive management of drug interactions and adverse effects. This article includes an extensive discussion of drug interactions involving antiretroviral agents and other medications (eg, antibiotics, oral contraceptives, H2 antagonists, and lipid-lowering agents) commonly used in i...
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Osteoporotic fractures are an important public health problem with significant individual and societal costs. In addition to the major risk factors for osteoporotic fracture, low bone mineral density (BMD), age, low body weight and history of fracture or falls, some drugs are now considered to be important secondary risk factor for bone loss and fracture, particularly amongst predisposed indivi...
متن کاملAdverse effects of antiretroviral therapy for HIV infection: a review of selected topics.
In the current era of HIV treatment, the toxicity profiles of antiretroviral drugs have increasingly emerged as a basis for selecting initial antiretroviral regimens as well as a reason for switching therapy in treatment-experienced patients. In this respect, an intensive research effort involving clinical research as well as basic science research over the past six years, has focused on the cl...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2011
ISSN: 0025-6196
DOI: 10.4065/mcp.2011.0341